Cate Blanchett (Elizabeth I, Queen of England),
Geoffrey Rush (Sir Francis Walsingham),
Jordi Mollà (King Philip II of Spain),
Abbie Cornish (Elizabeth Throckmorton),
Laurence Fox (Sir Christopher Hatton),
Adam Godley (William Walsingham),
Tom Hollander (Amyas Paulet),
Kelly Hunter (Ursula Walsingham),
Rhys Ifans (Robert Reston),
Samantha Morton (Mary, Queen of Scots),
Clive Owen (Sir Walter Raleigh),
Adrian Scarborough (Calley),
John Shrapnel (Lord Howard),
Sam Spruell (Torturer),
David Sterne (Cellarman),
David Threlfall (Dr. John Dee),
Eddie Redmayne (Anthony Babington),
Robert Cambrinus (Count Georg von Helfenstein),
Christian Brassington (Archduke Charles),
Vidal Sancho (Spanish Minister)